| Sceletium
tortosoum was used by South African pastoralists and
hunter-gatherers as a mood substance from early times.
The traditionally prepared dried plant material was often
chewed into a quid, and the saliva swallowed, but it has
also been made into teas and tinctures. It has been reported
that it used to be inhaled as a snuff, or smoked, with
the addition of other herbs.
Sceletium
elevates mood and decreases anxiety, stress and tension.
The active constituents of the plant are alkaloids,
including mesembrine, mesembrenone, mesembrenol and
turtuosamine. Mesembrine is the major alkaloid present
in Sceletium and has been demonstrated to be a very
potent serotonin-uptake inhibitor. Intoxicating doses
can cause euphoria, initially with stimulation and later
with sedation. Sceletium is not a hallucinogenic.
People
taking any psychiatric drug (including all anxiety drugs,
sedatives, hypnotics, anti-depressants and anti-psychotics
and so-called designer or recreation drugs) or any cardiac
medications, are advised not to take any Sceletium-containing
products. As with most supplements and modern drugs,
safety in pregnancy has not been established. |
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